Jonathan Jimenez

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Receptors for vasoactive intestinal peptide (VIP) have been characterized in rat lymphoid cells. The interaction of [125I] VIP with blood mononuclear cells was rapid, reversible, specific and saturable. At apparent equilibrium, the binding of [125I] VIP was competitively inhibited by native VIP in the 0.01-100 nM range concentration. The binding data were(More)
It has previously been shown that stimulation of muscarinic m1 or m3 receptors can, by generating diacylglycerol (DAG) and activating protein kinase C (PKC), accelerate the breakdown of the amyloid precursor protein (APP) to form soluble, non-amyloidogenic peptides (APPs). This relationship has been demonstrated in human glioma and neuroblastoma cells as(More)
We studied the response of type II thyroxine 5'-deiodinase (5'-D) activity to superior cervical ganglionectomy (SCGX) or adrenalectomy (ADX) in the rat pineal gland and other tissues. The results show that no difference was found between controls and SCGX animals during the day, but at night, SCGX modified the day-night cycle of 5'-D activity in the pineal(More)
A non-ionic detergent such as Lubrol-PX extracts in soluble form the VIP-binding structures of rat liver plasma membranes. Detergent-solubilized proteins bind specifically [125I]VIP and the complex tracer-protein is identified by the use of Sepharose 6B columns. The interaction is only possible in the absence of detergent (below 0.001%) and is inhibited by(More)
Intact yeast cells subjected to a punctual electric field (in an electroporator) can be transformed with exogenous DNA (1), indicating that DNA molecules can move into the cell through the cell wall. In pulsed-field electrophoresis, we have also observed that removal of the cell wall is an unnecessary step for the large chromosomal DNA molecules (ranging(More)
  • Obs P M P N R P B Corr, P M P N R P B Obs, +8 authors Respectivement Pré
  • 2012
La seconde étape consiste à établir des projections sur les croissances futures du produit intérieur brut (PIB) et des dettes de différents pays. L'idée retenue initialement était de trouver un modèle, relativement simple, permettant de projeter ces grandeurs macroéco-nomiques : le choix de la projection de l'évolution des dettes s'explique par le fait(More)
The regulation by alpha- and beta-adrenergic agonists of pineal N-acetyltransferase (NAT) and type II thyroxine 5'-deiodinase (5'-D) in rats at either 2 or 6 weeks of age was studied. The pattern of stimulation was different because NAT activity could be clearly activated by an alpha-adrenergic agonist, phenylephrine, only in 2-week-old rats. However,(More)
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