Jonathan Cole

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The role of proprioception in the control and adaptation of visuomotor relationships is still unclear. We have studied a deafferented subject, IW, and control subjects in a task in which they used single joint elbow extension to move to a visual target, with visual feedback of the terminal position provided by a cursor displayed in the plane of their(More)
In order to investigate the ways in which sensory channels interact to control balance, we measured the postural response evoked by galvanic vestibular stimulation (GVS) in a rare subject (I. W.) with a large-fibre sensory neuronopathy. I. W. has no sensations of cutaneous light touch and movement/position sense below the neck, and without vision he has no(More)
It is unclear how knowledge of one's actions and one's body contribute to the understanding of others' actions. Here we show that two subjects lacking cutaneous touch and sense of movement and position show a selective deficit in interpreting another person's anticipation of weight when seeing him lifting boxes. We suggest that this ability occurs through(More)
We evaluated the gait pattern of a deafferented subject who suffered a permanent loss of large sensory myelinated fibers below the neck following an acute episode of purely sensory neuropathy 21 years ago. The subject has developed several strategies to achieve a secure gait, namely: (1) a reduction of the degrees of freedom by freezing the knee(More)
Many types of sensory information are known to contribute to the human balance control process but little is known about how the different sensory channels interact. Here we consider the postural response to a perturbation delivered to the vestibular channel using galvanic vestibular stimulation. We show that the response is modified by the absence of(More)
A subject lacking proprioceptive and tactile sensibility below the neck and a group of control subjects performed sequences of periodic finger taps involving a pattern of accentuation. The required intertap interval was 700 ms. In some situations, the taps were synchronized with the clicks of a metronome. Feedback conditions were manipulated by either(More)
A previous functional magnetic resonance imaging (fMRI) study of an A-beta deafferented subject (GL) showed that stimulation of tactile C afferents (CT) activates insular cortex whereas no activation was seen in somatosensory cortices. Psychophysical studies suggested that CT afferents contribute to affective but not to discriminative aspects of tactile(More)
A weight discrimination study was undertaken to test (i) the capacity of controls and a deafferented subject (deprived of large sensory myelinated fibres from nose down), to discriminate weights with and without vision; (ii) the capacities of observers to discriminate weights while watching the deafferented and control subjects' lifting movements; (iii) the(More)
The role of sensory feedback in the control of movements was investigated in two deafferented patients with complete loss of cutaneous touch and movement/position sense below the neck and two control groups of different ages. In a synchronized repetitive finger-tapping task in time with a regular auditory pacing signal, the deafferented participants showed(More)
Human subjects can pre-program movements on the basis of visual cues. Experience in a particular task leads to the storage of appropriate control parameters which are used in programming subsequent movements, via a short-term motor memory. The form, duration and usage of this memory are, however, uncertain. Repetitive wrist flexion and extension movements(More)