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PURPOSE To provide evidence-based guidance on the optimum prevention and treatment approaches in the management of chemotherapy-induced peripheral neuropathies (CIPN) in adult cancer survivors. METHODS A systematic literature search identified relevant, randomized controlled trials (RCTs) for the treatment of CIPN. Primary outcomes included incidence and… (More)
Single unit recordings were made from the nerve branch innervating the crista in the horizontal semicircular canal of a pigeon. The vestibular organ was either stimulated with sound through the ear canal or with a vibrator in contact with the membraneous ampulla roof. Units responding to sound or vibration showed tuning with a best frequency of… (More)
In a previous paper attention was drawn to the possibility of introducing the labyrinth as an organ for sound perception. Behavioural responses of the guinea pig as well as electrophysiological results in the pigeon indicated that fenestration of the labyrinth might be an alternative to cochlear implants. In this paper gross electrode electrophysiological… (More)
Hearing thresholds were measured for 5 normal pigeons with the heart-rate conditioning method. After extirpation of the membranous cochlea on both sides and fenestration of the lateral canals, hearing thresholds were measured again with the same method at 250, 750 and 1500 Hz. Hearing thresholds found in this way for deaf fenestrated pigeons correspond very… (More)
Cochlea-deprived pigeons were placed on a rotating platform and stimulated with sound after fenestration of the lateral canal. The whole nerve action potentials evoked by the sound stimulus were suppressed by the rotatory stimulus. The time course of this suppression makes the lateral crista the most acceptable site of generation of the action potential. In… (More)
A serological study using the complement fixation reaction for herpes zoster virus (HZV) and herpes simplex virus (HSV) was carried out on 120 patients with Bell's palsy and 5 with Ramsay-Hunt syndrome. Three Bell's palsy patients (2.5%) showed a significant HZV antibody titre rise. In no case was a rise of HSV antibody titre observed. Two Ramsay-Hunt… (More)
A 37-year-old woman had peripheral facial palsy. It took nearly two weeks to establish the syphilitic origin. This rare disease is discussed with reference to nine cases reported in the literature since 1945. The prognosis is good with early antibiotic therapy.