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  • Michael C Heinrich, Christopher L. Corless, +15 authors Jonathan Alfred Fletcher
  • Medicine
  • Journal of clinical oncology : official journal…
  • 2003 (First Publication: 1 December 2003)
  • PURPOSE Most gastrointestinal stromal tumors (GISTs) express constitutively activated mutant isoforms of KIT or kinase platelet-derived growth factor receptor alpha (PDGFRA) that are potentialExpand
  • Michael C Heinrich, Robert G Maki, +12 authors George D. Demetri
  • Medicine
  • Journal of clinical oncology : official journal…
  • 2008 (First Publication: 20 November 2008)
  • PURPOSE Most gastrointestinal stromal tumors (GISTs) harbor mutant KIT or platelet-derived growth factor receptor alpha (PDGFRA) kinases, which are imatinib targets. Sunitinib, which targets KIT,Expand
  • Fabiola Bertu Medeiros, Christopher L. Corless, +5 authors Christopher D. M. Fletcher
  • Medicine
  • The American journal of surgical pathology
  • 2004 (First Publication: 1 July 2004)
  • The diagnosis of gastrointestinal stromal tumor (GIST) is currently based on morphologic features and immunohistochemical demonstration of KIT (CD117). However, some tumors (in our estimationExpand