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  • Jonas V. Schaefer, Andreas Plückthun
  • Biology, Medicine
  • Journal of molecular biology
  • 2012 (First Publication: 1 April 2012)
  • Aggregation is an important concern for therapeutic antibodies, since it can lead to reduced bioactivity and increase the risk of immunogenicity. In our analysis of immunoglobulin G (IgG) moleculesContinue Reading
  • Michal Nemergut, Gabriel Žoldák, +4 authors Erik Sedlák
  • Chemistry, Medicine
  • Protein science : a publication of the Protein…
  • 2017 (First Publication: 1 November 2017)
  • Monoclonal antibodies of the immunoglobulin G (IgG) type have become mainstream therapeutics for the treatment of many life-threatening diseases. For their successful application in the clinic and aContinue Reading
  • Syafrizayanti, Smiths S. Lueong, Cuixia Di, Jonas V. Schaefer, Andreas Plückthun, Jörg D Hoheisel
  • Medicine, Biology
  • Scientific reports
  • 2017 (First Publication: 3 January 2017)
  • DNA sequencing has advanced to a state that permits studying the genomes of individual patients as nearly a matter of routine. Towards analysing a tissue's protein content in a similar manner, weContinue Reading