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Functional connectivity (FC) as measured by correlation between fMRI BOLD time courses of distinct brain regions has revealed meaningful organization of spontaneous fluctuations in the resting brain. However, an increasing amount of evidence points to non-stationarity of FC; i.e., FC dynamically changes over time reflecting additional and rich information(More)
Functional connectivity analysis of fMRI data can reveal synchronised activity between anatomically distinct brain regions. Here, we extract the characteristic connectivity signatures of different brain states to perform classification, allowing us to decode the different states based on the functional connectivity patterns. Our approach is based on(More)
In the past years, mass univariate statistical analyses of neuroimaging data have been complemented by the use of multivariate pattern analyses, especially based on machine learning models. While these allow an increased sensitivity for the detection of spatially distributed effects compared to univariate techniques, they lack an established and accessible(More)
The brain can be regarded as a network: a connected system where nodes, or units, represent different specialized regions and links, or connections, represent communication pathways. From a functional perspective, communication is coded by temporal dependence between the activities of different brain areas. In the last decade, the abstract representation of(More)
The observation and description of the living brain has attracted a lot of research over the past centuries. Many noninvasive imaging modalities have been developed, such as topographical techniques based on the electromagnetic field potential [i.e., electroencephalography (EEG) and magnetoencephalography (MEG)], and tomography approaches including positron(More)
In this paper we present a text independent on-line writer identification system based on Gaussian Mixture Models (GMMs). This system has been developed in the context of research on Smart Meeting Rooms. The GMMs in our system are trained using two sets of features extracted from a text line. The first feature set is similar to feature sets used in(More)
Multiple sclerosis (MS), a variable and diffuse disease affecting white and gray matter, is known to cause functional connectivity anomalies in patients. However, related studies published to-date are post hoc; our hypothesis was that such alterations could discriminate between patients and healthy controls in a predictive setting, laying the groundwork for(More)
Simple weighted undirected graphs with a fixed number of vertices and fixed vertex orderings can be used to represent data and patterns in a wide variety of scientific and engineering domains. Classification of such graphs by existing graph matching methods perform rather poorly because they do not exploit their specificity. As an alternative, methods(More)
The clinical picture associated with 22q11.2 deletion syndrome (22q11DS) includes mild mental retardation and an increased risk of schizophrenia. While the clinical phenotype has been related to structural brain network alterations, there is only scarce information about functional connectivity in 22q11DS. However, such studies could lead to a better(More)