Jonas Martinsson

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The M2 protein is a small, single-span transmembrane (TM) protein from the influenza A virus. This virus enters cells via endosomes; as the endosomes mature and become more acidic M2 facilitates proton transport into the viral interior, thereby disrupting matrix protein/RNA interactions required for infectivity. A mystery has been how protons can accumulate(More)
Structure-based protein design offers a possibility of optimizing the overall shape of engineered binding scaffolds to match their targets better. We developed a computational approach for the structure-based design of repeat proteins that allows for adjustment of geometrical features like length, curvature, and helical twist. By combining sequence(More)
Extreme Programming (XP) and the Capability Maturity Model (CMM) are two recently emerging models addressing the difficulty of developing and delivering high-quality software products. The CMM introduces 5 levels of maturity and gives guidelines for what to do at an organizational level, while XP gives explicit guidelines for how to develop software at a(More)
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