Jon S Lawrence

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The atmospheric conditions above Dome A, a currently unmanned location at the highest point on the Antarctic plateau, are uniquely suited to astronomy. For certain types of astronomy Dome A is likely to be the best location on the planet, and this has motivated the development of the Plateau Observatory (PLATO). PLATO was deployed to Dome A in early 2008.(More)
One of the most important considerations when planning the next generation of ground-based optical astronomical telescopes is to choose a site that has excellent 'seeing'--the jitter in the apparent position of a star that is caused by light bending as it passes through regions of differing refractive index in the Earth's atmosphere. The best mid-latitude(More)
The AASTINO (Automated Astrophysical Site Testing INternational Observatory) is a remote laboratory that has been operating at Dome C station on the Antarctic plateau since January 2003. It is designed to run throughout the Antarctic winter without intervention, and to collect data on the astronomical qualities of the site. A Stirling engine and a pair of(More)
Peptide/MHC tetrameric complexes were used to enumerate the frequency of HLA class I-restricted epitope-specific CD8+ T cells in 18 HLA-A*0201 HIV type 1-infected asymptomatic patients. HLA-A*0201 molecules were complexed to HIV Gag p17 (amino acids 77-85) and reverse transcriptase (amino acids 464-472) peptides, biotinylated, and bound to(More)
OBJECTIVE Our prespecified dose-response analyses of A Very Early Rehabilitation Trial (AVERT) aim to provide practical guidance for clinicians on the timing, frequency, and amount of mobilization following acute stroke. METHODS Eligible patients were aged ≥18 years, had confirmed first (or recurrent) stroke, and were admitted to a stroke unit within 24(More)
The best ground-based astronomical sites in terms of telescope sensitivity at infrared and submillimeter wavelengths are located on the Antarctic Plateau, where high atmospheric transparency and low sky emission are obtained because of the extremely cold and dry air; these benefits are well characterized at the South Pole station. The relative advantages(More)
Over a decade of site testing in Antarctica has shown that both South Pole and Dome C are exceptional sites for astronomy, with certain atmospheric conditions superior to those at existing mid-latitude sites. However, the highest point on the Antarctic plateau, Dome A, is expected to experience colder atmospheric temperatures, lower wind speeds, and a(More)
The near infrared sky spectral brightness has been measured at the South Pole with the Near Infrared Sky Monitor (NISM) throughout the 2001 winter season. The sky is found to be typically more than an order of magnitude darker than at temperate latitude sites, consistent with previous South Pole observations. Reliable robotic operation of the NISM, a low(More)
The PLATeau Observatory (PLATO) is an automated self-powered astrophysical observatory that was deployed to Dome A, the highest point on the Antarctic plateau, in 2008 January. PLATO consists of a suite of site-testing instruments designed to quantify the benefits of the Dome A site for astronomy, and science instruments designed to take advantage of the(More)
While definitive winter measurements for Dome C must await until 2004, on the basis of existing data the Antarctic Dome sites promise the best conditions on the Earth for many astronomical observations. Because atmospheric turbulence is largely confined to a ~ 100 m ground layer, adaptive correction with a single deformable mirror conjugated to this layer(More)