Jon R. Ausobsky

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We measured the phagocytic capacity of the reticulo-endothelial system by assay of the clearance of colloidal carbon from the blood stream in both normal mice and mice in which shock had been induced by intraperitoneal injection of hypertonic glucose. The group of shocked mice was further subdivided into those pretreated with the immunoadjuvant, muramyl(More)
A prospective randomized controlled clinical trial is reported which compares midline with lateral paramedian incisions in relation to the development of incisional hernias at one year. Of 431 patients randomized, 329 were available for assessment one year later. Two patients suffered burst abdomen, both being in the lateral paramedian group. Twenty-two(More)
We studied the relationship between cell-mediated immunity (assessed by preoperative skin reactions to four recall antigens) and postoperative infective complications in 166 patients undergoing major laparotomies. They were randomly allocated to receive 150 mg of levamisole or placebo on the day of operation and for the following 2 days; their course was(More)
INTRODUCTION Acute cholecystitis is among the most common general surgical presentations. There is a cohort of patients who develop systemic sepsis and complications of acute cholecystitis. These patients are often elderly and co-morbid. Conservative management with percutaneous cholecystostomy has been shown to be a safe and effective management option in(More)
We compared the incidence of wound failure (burst abdomen and incisional herniation up to 4 years after operation) in a consecutive series of 282 major laparotomies closed with continuous monofilament nylon, and randomly allocated to mass (all layers except skin) or layered (anterior and posterior aponeuroses separately sutured) techniques. Surgeons were(More)
Twenty-five patients undergoing elective surgery for large abdominal aortic aneurysms (AAAs) were investigated by preoperative ultrasonography (US), computed tomography (CT) or intravenous digital subtraction angiography (IV-DSA). The accuracy of each modality in assessing the upper and lower extent of aneurysmal disease was then compared. IV-DSA proved(More)
Monofilament nylon suture material undergoes both plastic and elastic elongation when stretched. Nylon inserted as a continuous suture for approximation of the abdominal musculo-aponeurosis may, therefore, allow early separation of the cut edges, which may predispose to the later development of an incisional hernia. This hypothesis was tested in a(More)
The role of preoperative localisation tests before initial neck exploration for primary hyperparathyroidism (PHP) remains controversial, as does the optimal surgical approach. We report our experience with preoperative ultrasound (US) and the operative management of sporadic PHP between 1990 and 1995. Preoperative US was carried out by an experienced(More)
There has been steady increase in demand for laparoscopic colonic resection as benefits are manifold compared to open and include smaller incisions, less pain, quicker recovery and convalescence, reduced morbidity and reduced analgesic demands. We devised a preceptorship programme with the aim of all four coloproctologists in our unit becoming proficient(More)
CONTEXT Pancreatic body carcinoma has a poor prognosis with advanced disease at presentation. Recent experience at multidisciplinary team (MDT) meetings suggests increasing prevalence. OBJECTIVE Our aim was to determine if introduction of MDT meetings has affected the natural history of this disease. DESIGN Retrospective diagnostic and survival data(More)