Jon-Paul Griffiths

Learn More
The reduction in doctors' hours and the introduction of specialist training have reduced general surgical training by 60%. This study assessed the implications for a single health board. A questionnaire listing 13 representative operations was sent to 44 trainees and 52 trainers to determine the number of operations a trainee should perform. The total(More)
The impact of past and current asthma on ventilatory function was assessed among young adults born in Britain March 3-9, 1958 who had been followed from birth to ages 7, 11, 16, 23, and 33 yr. We compared 1,060 subjects with a history of asthma, wheezy bronchitis, or wheezing with 275 control subjects with no history of chest illness. Forced expiratory(More)
Epidermal growth factor (EGF ) from mouse submaxillary glands is ;I polypeptide o f hi, 00.15 which stimulates cpithelial cell proliferation ;ind which inhibits gastric acid secretion both i t i iii.o I I I a n d i r i ~ i i r o 12. 3 I. Inhibition o f pepsinogen secretion b y k<iF has been observed i t i t i i v 14 I. but this effect could be secondary t o(More)
The aim of this study was to determine the feasibility of assessing surgical training from routine, prospectively collected data and to establish whether weighted workload assessed surgical training more objectively than caseload (case counting). The surgeons in this surgical unit prospectively documented details of all operations and endoscopic procedures(More)
Syntheses of enantiopure organosulfur donors by three different strategies requiring only four-six steps are reported. The key step involves either double substitution of an enantiopure cyclic sulfate ester by a dithiolate, attachment of a chiral diol as a ketal, or completely diastereoselective cycloaddition of 1,3-dithiole-2,4,5-trithione to an(More)