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Neuronal plasticity and synaptic remodeling play important roles during the development of the invertebrate nervous system. In addition, structural neuroplasticity as a result of long-term environmental changes, behavioral modifications, age, and experience have been demonstrated in the brains of sexually mature insects. In adult vertebrates, persistent(More)
Macrophage-like U-937 cells secrete a 22-kilodalton heparin-binding growth factor that is mitogenic for BALB-3T3 fibroblasts and smooth muscle cells, but not endothelial cells. The amino acid sequence predicted from complementary DNA clones indicates that the mitogen is a new member of the epidermal growth factor (EGF) family. This heparin-binding EGF-like(More)
Prion protein (PrP), which is involved in the pathogenesis of scrapie, occurs in 2 forms. The form extracted from scrapie brain is protease resistant (PrP-res), whereas PrP from normal brain is protease sensitive (PrP-sen). This study examined whether PrP-res could be detected in brains of sheep with scrapie by immunohistochemistry (IHC). A suitable IHC(More)
Ovine scrapie is a member of the transmissible spongiform encephalopathies (TSEs), a heterogeneous family of fatal neurologic disorders characterized by deposition of an abnormal isoform (prion protein [PrP] PrP-Sc) of a cellular sialoglycoprotein in neural tissue. PrP-Sc is detectable in some lymphoid tissues of infected sheep months or years before(More)
The effect of alternative family structures on children's educational and occupational success has been constant over the past 30 years. Higher rates of unemployment and lower-status occupational positions could account for the negative effect of single-mother families on children's attainment throughout the period. Children from single-father families and(More)
We present the results of the timing and color analysis of more than two hundred RXTE/PCA observations of the bright black-hole transient GX 339–4 obtained during its 2002/2003 outburst. The color-intensity evolution of the system, coupled to the properties of its fast time variability, allow the identification of four separate states. Depending on the(More)
The properties of the orbit and the donor star in the high mass X-ray binary microquasar LS 5039 indicate that accretion processes should mainly occur via a radiatively driven wind. In such a scenario, significant X-ray variability would be expected due to the eccentricity of the orbit. The source has been observed at X-rays by several missions, although(More)
Subject headings: Black hole physics – relativity – stars: binaries – physical data and processes: accretion disks ABSTRACT Cool thermal emission components have recently been revealed in the X-ray spectra of a small number of ultra-luminous X-ray (ULX) sources with L X ≥ 10 40 erg/s in nearby galaxies. These components can be well fitted with accretion(More)
We have analyzed an XMM-Newton observation of the nearby spiral galaxy NGC 1313, which contains two " ultra-luminous " X-ray (ULX) sources. We measure isotropic luminosities of L X = 2.0 × 10 40 erg s −1 and L X = 6.6 × 10 39 erg s −1 for NGC 1313 X-1 and X-2 (0.2-10.0 keV, assuming a distance of 3.7 Mpc). The spectra statistically require soft and hard(More)