Jon Helgestad

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A prospective, population-based registration of children with immune thrombocytopenic purpura (ITP) was performed in Norway in 1996 and 1997. Ninety-two cases were identified, indicating an incidence of 5.3 per 100,000 children under 15 years. The sex ratio (female/male) was 1.2/1. Fifty-six percent presented with cutaneous signs only. The lowest platelet(More)
Cerebral atypical teratoid/rhabdoid tumors (AT/RT) of infancy are highly malignant and have a poor prognosis. The authors report on one case with long-term survival. The patient was a 1 year-old boy presenting with a large AT/RT in the right temporal lobe. He was treated with complete surgery, followed by multiagent chemotherapy. Later he had a second(More)
UNLABELLED ESSENTIALS: Children with acute lymphoblastic leukemia (ALL) are at risk of thromboembolism (TE). This is a prospective evaluation of the incidence, risk factors and outcomes of TE in 1038 children with ALL. TE occurred in 6.1% of children, with the highest incidence (20.5%) among those aged 15-17 years. A TE-associated case fatality of 6.4%(More)
BACKGROUND This retrospective study of 12 children with cerebral or skull base tumors was undertaken to evaluate morbidity and outcome after gamma-knife surgery. PROCEDURE Twelve consecutive children treated with stereotactic radiosurgery in a curative intent were reviewed. There were five girls and seven boys. The mean age at diagnosis was 5.8 years and(More)
Survival data for all consecutive paediatric cancer patients (age 0-15) diagnosed between 1 January 1992 and 31 December 2001 are presented. The patients came from a catchment area in Norway with a population of approximately 1 million. During the period under review, the most intensive paediatric cancer treatment regimen up until now was given. There were(More)
of deregulation than the differentially expressed genes from the comparison TET2 mutated versus wild type (Figure 1 b; Supplementary Figure 1 and Supplementary Tables 2 and 3). These results indicate that 5hmC levels are most likely a more relevant measurement to define biologically distinct secondary leukemia subtypes than the TET2 (or IDH1/2) mutational(More)
Data on the validity of pediatric thrombosis diagnoses are missing. We aimed to examine the predictive value of a diagnosis of venous and arterial thrombosis using the Danish National Patient Registry (DNPR). We identified all first-time diagnoses among children and adolescents (aged 0-18 years) between 1994 and 2006 in DNPR. In total, 1138 potential cases(More)
Persons with glucose-6-phosphate dehydrogenase (G6PD) deficiency may suffer episodesof acutehemolysis triggeredby infection, drugs, andchemicals [1]. Acute favism after ingestion of fava beans is a special type [2]. Recently, two caseswith clinically manifest methemoglobinemia, a hitherto unrecognized feature, were reported [3, 4]. We saw two similar(More)
The present retrospective study includes all children suspected for having neuroblastoma, admitted to Odense University Hospital in September 1984 through December 1993. Thirty-six children at the age range of 1 month to 14 years and 10 month were investigated with 123I-metaiodobenzylguanidine (MIBG). Nineteen children had histologically verified(More)