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Subject-specific artifacts caused by head motion and physiological noise are major confounds in BOLD fMRI analyses. However, there is little consensus on the optimal choice of data preprocessing steps to minimize these effects. To evaluate the effects of various preprocessing strategies, we present a framework which comprises a combination of (1)(More)
The effects of physiological noise may significantly limit the reproducibility and accuracy of BOLD fMRI. However, physiological noise evidences a complex, undersampled temporal structure and is often non-orthogonal relative to the neuronally-linked BOLD response, which presents a significant challenge for identifying and removing such artifact. This paper(More)
  • Jon Erik Ween
  • 2008
Functional imaging is beginning to outline the brain's functional architecture and mechanisms of recovery from injury. I will review primarily the motor-function literature from normal populations, learning trials, stroke recovery, and rehabilitation with a neural network approach that may prove fruitful in further advancing our understanding of brain(More)
Prospective memory (PM) is the ability to carry out a planned intention at a future time. We studied PM deficits in a group of community-dwelling stroke survivors compared with normal controls. Twelve stroke patients and 12 matched controls performed a series of tests assessing executive function, prospective (PM) and retrospective memory (RM). Patients(More)
Prevention and treatment of poststroke depression with mirtazapine in patients with acute stroke. Q Does treatment with mirtazapine after an ischaemic stroke prevent onset of depression? METHODS Design: Randomised controlled trial. Patients: Seventy people who had suffered an ischaemic stroke, confirmed by MRI or CT scan. People were excluded if they were(More)
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