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Illness severity scores have become widely used in neonatal intensive care. Primarily this has been to adjust the mortality observed in a particular hospital or population for the morbidity of their infants, and hence allow standardised comparisons to be performed. However, although risk correction has become relatively commonplace in relation to audit and(More)
OBJECTIVE To assess changes in survival for infants born before 26 completed weeks of gestation. DESIGN Prospective cohort study in a geographically defined population. SETTING Former Trent health region of the United Kingdom. SUBJECTS All infants born at 22+0 to 25+6 weeks' gestation to mothers living in the region. Terminations were excluded but all(More)
AIMS To investigate the extent of socioeconomic inequalities in the incidence of very preterm birth over the past decade. METHODS Ecological study of all 549 618 births in the former Trent health region, UK, from 1 January 1994 to 31 December 2003. All singleton births of 22(+0) to 32(+6) weeks gestation (7 185 births) were identified from population(More)
AIM Heated humidified high-flow nasal cannula (HHHFNC) oxygen is a relatively new form of respiratory support and is increasing in popularity despite lack of supportive evidence and amid safety concerns. We investigated the prevalence of its use in tertiary neonatal units in the UK. METHOD Electronic survey. RESULTS A total of 57 units were contacted(More)
OBJECTIVE To describe neonatal outcomes and explore variation in delivery of care for infants born late (34-36  weeks) and moderately (32-33 weeks) preterm (LMPT). DESIGN/SETTING Prospective population-based study comprising births in four major maternity centres, one midwifery-led unit and at home between September 2009 and December 2010. Data were(More)
BACKGROUND Preterm birth is the most important single determinant of adverse outcome in the United Kingdom; one in every 70 babies (1.4%) is born before 32 weeks (very preterm), yet these births account for over half of infant deaths.Deferring cord clamping allows blood flow between baby and placenta to continue for a short time. This often leads to(More)
OBJECTIVE To describe feeding and gastrointestinal outcomes in growth-restricted infants <29 weeks' gestation and to determine the rate of feed advancement which they tolerate. DESIGN Analysis of prospectively collected data from a randomised feeding trial, the Abnormal Doppler Enteral Prescription Trial (ADEPT). SETTING 54 neonatal units in the UK and(More)
BACKGROUND Necrotizing enterocolitis (NEC) is the most common gastrointestinal (GI) emergency seen in neonatal units. Many factors have been considered as potentially important aetiologically, including gut ischaemia, sepsis and feeding. However, evidence remains equivocal. OBJECTIVE This study investigated whether preterm babies born to mothers with(More)