Jon Cohen

Publications957
h-index37
Citations7,863
Highly Influential Citations280
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Race to find COVID-19 treatments accelerates.
TLDR
The study will examine an experimental antiviral compound called remdesivir; the malaria medication chloroquine (or its chemical cousin hydroxychloroquine); a combination of the HIV drugs lopinavir and ritonavir; and that combination plus interferon-beta, an immune system messenger that can help cripple viruses.
Superantigens: microbial agents that corrupt immunity.
Countries test tactics in 'war' against COVID-19.
TLDR
The hastily introduced measures vary widely between countries and even within countries, and reflect different phases of the epidemic, as well as differences in resources, cultures, governments, and laws.
New SARS-like virus in China triggers alarm.
TLDR
After criticism surfaced about potential delays in sharing information, Chinese scientists have made six sequences of the virus available, which has allowed other researchers to rapidly develop diagnostic tests and begin synthesizing the virus so it can be studied in animal markets.
A randomized, double-blind, placebo-controlled trial of TAK-242 for the treatment of severe sepsis*
TLDR
TAK-242 failed to suppress cytokine levels in patients with sepsis and shock or respiratory failure, and treatment with TAK-242 resulted in mild increases in serum methemoglobin levels but was otherwise well tolerated.
Can China's COVID-19 strategy work elsewhere?
TLDR
A key feature was the lockdown in many cities in Hubei, which restricted much of the transmission to households, where the virus eventually burned out and prevented potentially hundreds of thousands of cases in other provinces.
Wuhan seafood market may not be source of novel virus spreading globally
Vaccine designers take first shots at COVID-19.
TLDR
The race to develop a vaccine against the novel coronavirus is unprecedented in speed, scale, and scope; the "platforms" include inactivated and attenuated viruses, protein subunits, harmless viral vectors, messenger RNA, DNA, and viruslike particles.
HIV/AIDS: India Slashes Estimate of HIV-Infected People
TLDR
After more extensive sampling, including a national household survey, the Indian government has come up with a new estimate that reduces the number of HIV-infected people by more than half.
The New World of Global Health
An array of well-heeled new players has dramatically reshaped how wealthy countries tackle infectious diseases of the poor. But increasingly, these ambitious efforts are confronting their own…
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