Jon Casey Berridge

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the development of mixture designs and retention mapping and their general application to opti-misation problems. It is interesting to compare a later paper (Coenegracht et al.) which explores the use of multicriteria decision-making methods with various retention mapping procedures based on different approaches varying mobile phase composition. The next(More)
We have used both a rat orthotopic hepatocellular carcinoma model and a mouse allograft tumor model to study liver tumor ablation with nanosecond pulsed electric fields (nsPEF). We confirm that nsPEF treatment triggers apoptosis in rat liver tumor cells as indicated by the appearance of cleaved caspase 3 and 9 within two hours after treatment. Furthermore(More)
BACKGROUND We have been developing a non-thermal, drug-free tumor therapy called Nano-Pulse Stimulation (NPS) that delivers ultrashort electric pulses to tumor cells which eliminates the tumor and inhibits secondary tumor growth. We hypothesized that the mechanism for inhibiting secondary tumor growth involves stimulating an adaptive immune response via an(More)
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