Jon A. Schwartz

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The sea slug Elysia clarki sequesters photosynthetically functional chloroplasts from at least a dozen algal species and maintains these plastids for up to 4 months. Elysia papillosa and Placida kingstoni also feed on some of the same, or congeneric species such as Bryopsis plumosa and Penicillus lamourouxii, but cannot maintain plastids longer than 2(More)
PURPOSE Gold nanoshells (NSs) have already shown great promise as photothermal actuators for cancer therapy. Integrin αvβ3 is a marker that is specifically and preferentially overexpressed on multiple tumor types and on angiogenic tumor neovasculature. Active targeting of NSs to integrin αvβ3 offers the potential to increase accumulation preferentially in(More)
A high-voltage (HV) integrated circuit has been demonstrated to transport fluidic droplet samples on programmable paths across the array of driving electrodes on its hydrophobically coated surface. This exciter chip is the engine for dielectrophoresis (DEP)-based micro-fluidic lab-on-a-chip systems, creating field excitations that inject and move fluidic(More)
—In this paper, we have designed and fabricated a mi-crofluidic channel to focus biological cells using dielectrophoresis for cytometry applications. The device consists of an elliptic-like channel fabricated by isotropic etching of soda lime glass wafers and a subsequent wafer-bonding process. Microelectrodes are pat-terned on the circumference of the(More)
A high-voltage (HV) integrated circuit has been demonstrated to transport droplets on programmable paths across its coated surface. This chip is the engine for a dielectrophoresis (DEP)-based micro-fluidic lab-on-a-chip system. This chip creates DEP forces that move and help inject droplets. Electrode excitation voltage and frequency are variable. With the(More)
Current imaging techniques capable of tracking nanoparticles in vivo supply either a large field of view or cellular resolution, but not both. Here, we demonstrate a multimodality imaging platform of optical coherence tomography (OCT) techniques for high resolution, wide field of view in vivo imaging of nanoparticles. This platform includes the first in(More)
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