Jolanta Lisowiec-Wachnicka

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Antisense oligonucleotides have been studied for many years as a tool for gene silencing. One of the most difficult cases of selective RNA silencing involves the alleles of single nucleotide polymorphisms, in which the allele sequence is differentiated by a single nucleotide. A new approach to improve the performance of allele selectivity for antisense(More)
Herein, we present comprehensive physicochemical and structural analysis of various DNA hairpins modified with pyrrolo-2'-deoxycytidine (Py-dC) derivatives. The introduction of modified Py-dC in most cases causes minor decrease of hairpin thermodynamic stability. The energetically unfavorable effect is more pronounced when modified residue is present within(More)
The images for Figs 2–5 are incorrectly switched. The image that appears as Fig 2 should be Fig 5. The image that appears as Fig 3 should be Fig 2. The image that appears as Fig 4 should be Fig 3. The image that appears as Fig 5 should be Fig 4. The figure captions appear in the correct order. Copyright: © 2016 Magner et al. This is an open access article(More)
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