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Pathophysiology of low back pain during exposure to microgravity.
TLDR
Further studies of countermeasures are recommended to prevent excessive spinal elongation and disc expansion, reduce low back pain in microgravity, and simulate 1-G disc homeostasis, which may also help prevent HNPs postflight. Expand
Lumbar Spine Paraspinal Muscle and Intervertebral Disc Height Changes in Astronauts After Long-Duration Spaceflight on the International Space Station
TLDR
The data reveal lumbar spine PSM atrophy after long-duration spaceflight, and this project aims to promote spine health and prevent spinal injury during space missions and here on Earth. Expand
From the international space station to the clinic: how prolonged unloading may disrupt lumbar spine stability.
TLDR
It is observed that multifidus atrophy, rather than intervertebral disc swelling, is associated strongly with lumbar flattening and increased stiffness, which may elevate injury risk for astronauts upon return to gravity loading. Expand
Back pain in space and post-flight spine injury: Mechanisms and countermeasure development
TLDR
Quantitative results on morphological, biochemical, metabolic, and kinematic spinal changes in the lumbar spine may aid further development of countermeasures to prevent lumbare back pain in microgravity and reduce the incidence of herniated nucleus pulposus post-flight. Expand
RISK OF INTERVERTEBRAL DISC DAMAGE AFTER PROLONGED SPACE FLIGHT
TLDR
The data support the idea that decreased gravitational forces on the IVDs, during prolonged microgravity, increases their water content but decreases proteoglycan, which increases disk degeneration risk on Earth. Expand