Johnson Lwakatare

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Nucleic acid amplification techniques for the diagnosis of tuberculosis (TB) are rapidly being developed. Scant work, however, has focused on pericardial TB. Using cryopreserved specimens from a prior study of pericarditis, we compared PCR to culture and histopathology for the diagnosis of tuberculous pericarditis in 36 specimens of pericardial fluid and 19(More)
SETTING Large academic medical center in Tanzania. OBJECTIVES To determine the etiologies and outcomes of large pericardial effusions in HIV-infected and uninfected patients. DESIGN Prospective cohort study of patients admitted with new large pericardial effusions, confirmed echocardiographically. Patients had pericardial biopsies and drainage with(More)
OBJECTIVE To determine the pattern of echocardiographic diagnoses in HIV-infected patients presenting with cardiac symptoms at Muhimbili National Hospital in Dar es Salaam, Tanzania. METHODS Patients known to be HIV positive and with cardiac complaints were prospectively recruited from the Hospital's care and treatment centre as well as from the medical(More)
The clinical records of 702 patients starting antihypertensive treatment between 1985 and 1990 were collected and reviewed at the end of 1992. At the end of an average observation period of three years, 47% of the patients had dropped out of the cardiac clinic. The medication compliance of 146 patients was estimated by both interview method as well as by(More)
OBJECTIVE To determine the prevalence, correlates and prognostic implications of anaemia and iron deficiency (ID) in patients with heart failure (HF) in Tanzania. METHOD This was a cross-sectional and prospective observational study conducted at Muhimbili National Hospital in Dar es Salaam, Tanzania. Patients were ≥ 18 years of age, with HF defined(More)
OBJECTIVE This study aimed to describe the contemporary aetiology, clinical characteristics and mortality and its predictors in heart failure (HF) in Tanzania. METHODS Design; Prospective observational study. Setting; Cardiovascular Center of the Muhimbili National Hospital in Dar es Salaam, Tanzania. Patients ≥18 years of age with HF defined by the(More)
BACKGROUND Hypertension among diabetics is a well recognized cardiovascular risk factor. This study aimed at determining the prevalence of hypertension, its control and the prevalence of other cardiovascular risk factors among diabetic patients. METHODS We consecutively enrolled 150 adult diabetics. Their age, sex weight, height, blood pressure, fasting(More)
AIM. To assess prevalence, type and covariates of abnormal left ventricular (LV) geometry in untreated native Tanzanian patients with hypertension in relation to normotensive controls. METHODS. Echocardiography was performed in 161 untreated hypertensive outpatients and 80 normotensive controls at a tertiary hospital in Tanzania. Hypertensive heart disease(More)
Data on the magnitude and risk factors for hypertension in sickle cell anaemia (SCA) are limited. A retrospective analysis of individuals with SCA aged ≥15 years enrolled from 2004-2014 at Muhimbili National Hospital, Tanzania was conducted to determine the prevalence, incidence and risk factors for hypertension. A total of 1013 individuals with SCA were(More)
Isradipine (Lomir) a new dihydropyridine calcium antagonist was evaluated for its efficacy, tolerability and safety among mild to moderate Tanzanian hypertensives. Twenty nine patients (7 males and 22 females), mean age 42.7 +/- 8.5 years entered active treatment phase, of the 16 week open label therapeutic trial. A mean decrease from base line in supine(More)