The algorithm and the results of a blind multiuser detector using a machine learning technique called support vector machine (SVM) on a chaos-based code division multiple access system is presented in this paper. Simulation results showed that the performance achieved by using SVM is comparable to existing minimum mean square error (MMSE) detector under… (More)
BACKGROUND Preclinical data suggest that sunitinib enhances the efficacy of radiotherapy. We tested the combination of sunitinib and hypofractionated image-guided radiotherapy (IGRT) in a cohort of patients with historically incurable distant metastases. METHODS Twenty five patients with oligometastases, defined as 1-5 sites of active disease on whole… (More)
BACKGROUND Persistence of γ-H2AX after ionizing radiation (IR) or drug therapy is a robust reporter of unrepaired DNA double strand breaks in treated cells. METHODS DU-145 prostate cancer cells were treated with a chemical library ±IR and assayed for persistence of γ-H2AX using an automated 96-well immunocytochemistry assay at 4 hours after treatment.… (More)
— This paper presents the algorithms and the results of multiuser detectors (MUD) on a synchronous chaos-based code division multiple access system (CDMA), which uses chaotic sequences as the spreading codes. Popular linear and non-linear MUD algorithms such as the decorrelator detector, minimum mean square error (MMSE) detector and parallel interference… (More)
BACKGROUND The optimal technique for performing lung IMRT remains poorly defined. We hypothesize that improved dose distributions associated with normal tissue-sparing IMRT can allow safe dose escalation resulting in decreased acute and late toxicity. METHODS We performed a retrospective analysis of 82 consecutive lung cancer patients treated with… (More)
[This corrects the article DOI: 10.1371/journal.pone.0124329.].
BACKGROUND There is an urgent need for a robust, clinically useful predictive model for survival in a heterogeneous group of patients with metastatic cancer referred to radiation oncology. METHODS From May 2012 to August 2013, 143 consecutive patients with stage IV cancer were prospectively evaluated by a single radiation oncologist. We retrospectively… (More)