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Like protein folding and crystallization, the self-assembly of complexes is a fundamental form of biomolecular organization. While the number of methods for creating synthetic complexes is growing rapidly, most require empirical tuning of assembly conditions and/or produce low yields. We use coarse-grained simulations of the assembly kinetics of complexes(More)
The heterodimeric NKG2A/CD94 receptor delivers an inhibitory signal upon recognition of HLA-E molecules. In several studies it has been demonstrated that signalling via NKG2A/CD94 receptor significantly reduces T or NK cell cytotoxic activity and cytokine production. In hemat-opoietic stem cell transplantation, expression of NKG2A on NK and T cells has been(More)
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