John Whitcomb Shaffer

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Prevention of fractures in the patient with myelodysplasia is aided by minimizing disuse osteoporosis by continuing weight-bearing whenever possible. The presentation and treatment of lower extremity fractures in the postoperative myelodysplasic patient have been reviewed. After these fractures severe systemic dysfunction can occur. A clinical situation(More)
In a double-blind study of the comparative effectiveness of eight phenothiazines, 322 newly-admitted state psychiatric hospital patients requiring tranquilizing drug therapy were randomly assigned to treatment with one of the following drugs: chlorpromazine, thioridazine, triflupromazine, prochlorperazine, perphenazine, thiopropazate, trifluoperazine, and(More)
The early (3 months) and later (6 months) patterns of incorporation and bone formation have been evaluated histomorphometrically for different types of bone grafts; that is, vascularized and nonvascularized autografts with and without ciclosporin, and vascularized and nonvascularized dog leukocyte antigen (DLA)-mismatched allografts with and without(More)
Vascularized canine fibular autografts demonstrated improved biologic and mechanical characteristics 3 months after surgery when compared with nonvascularized controls. The vascularized proximal fibula maintained its overall architecture without bony collapse or significant bone turnover. The strength and stiffness of these grafts were approximately 40 per(More)
We retrospectively analyzed the postoperative neurological complications in 137 patients who underwent a posterior spine fusion for scoliosis and had concomitant somatosensory cortical evoked-potential spinal-cord monitoring. The patients were divided into three specific operative groups: group 1, forty-nine patients who had a Harrington rod with segmental(More)
A measure of youthful family attitudes, the Closeness to Parents Scale, has continued to be predictive of cancer among physicians in a prospective study of medical students. Nonetheless, questions have remained concerning the meaning and reliability of this measure and whether its predictive value is diminishing over time. Perhaps more important, it is(More)
A positive bone scan in an experimental model of bilateral ulna diaphyseal bone grafts demonstrated early bone repair in both vascularized and nonvascularized orthotopic ulna autografts. A positive bone scan did not correlate with the perfusion of the vascularized and nonvascularized grafts as measured by microangiograms done 1 week postoperatively. In this(More)
A three-stage Papineau protocol for the management of chronic pyogenic osteomyelitis was critically investigated in 13 prospectively treated patients with draining osteomyelitis. Stage I involved removal of nonviable tissue and retained metal. Stage II involved grafting of cancellous iliac bone. In Stage III skin coverage was accomplished. Infection was(More)
Controlled laboratory data demonstrate biologic and mechanical characteristics of orthotopically placed canine ulnar autografts. The pattern of bone repair was similar in vascular and nonvascular ulnar grafts beginning with resorption followed by appositional reactive bone formation. The time intervals in the sequence were accelerated in the vascularized(More)
Multiple neurilemomas in two patients show that these tumors may indeed be multiple, may involve the same nerve trunk, may occur over a period of years, and may involve different regions of the body. Twelve neurilemomas were removed from the right upper extremity of a patient over a 3-year period. They varied in size from 0.5 cm to 4 cm in diameter and had(More)