John Wheeler

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BACKGROUND Although asbestos in general is well known to cause a range of neoplastic and non-neoplastic human health effects, not all asbestos fiber types have the same disease-causing potential, and the mode of action (MOA) of specific types of asbestos and related fibers for various health outcomes are not well understood. OBJECTIVES A workshop was held(More)
In spring 1952, as John Wheeler neared the end of design work for the first thermonuclear explosion, he plotted a radical change of research direction: from particles and atomic nuclei to general relativity. With only one quantitative observational contact (the perihelion shift of Mercury) and two qualitative ones (the expansion of the universe and(More)
Predicting toxicity quantitatively, using Quantitative Structure Activity Relationships (QSAR), has matured over recent years to the point that the predictions can be used to help identify missing comparison values in a substance's database. In this manuscript we investigate using the lethal dose that kills fifty percent of a test population (LD₅₀) for(More)
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