John W. Strohbehn

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A computer-based system has been developed for the integration and display of computerized tomography (CT) image data in the operating microscope in the correct perspective without requiring a stereotaxic frame. Spatial registration of the CT image data is accomplished by determination of the position of the operating microscope as its focal point is(More)
The frameless stereotactic operating microscope has expanded the potential application of modern stereotaxis to procedures outside of the intracranial compartment by removing the constraint of a rigid frame. We studied seven patients all of whom had a history, examination, and imaging studies consistent with lumbosacral spinal pathology for which they(More)
Accuracy of a stereotactic operating microscope, by which imaging data may be superimposed on the operative field without a stereotactic frame, has been most limited by the resolution of imaging information. Using newer algorithms and pilot pole calibration of the digitizer, an error in registration of 2 mm and in contour display of 3 mm has been(More)
The Frameless Stereotactic Operating Microscope permits information from CT and MRI scans to be displayed in the operating microscope in the proper scale and perspective without using a mechanical frame in the process, when the microscope is positioned over the surgical field. This registration is currently done using fiducials that must be present when the(More)
A phase I clinical trial assessing the feasibility and safety of hyperthermia in combination with 192Ir brachytherapy (60 Gy) for the treatment of malignant glioma now includes 14 patients. Hyperthermia (42-43 degrees C at tumor margin for 60 min) has been induced using stereotactically implanted afterloading catheters and a microwave (915 or 2,450 MHz)(More)
An oncolytic effect of hyperthermia in the 42 degrees to 43 degrees C range has been previously demonstrated in cell culture and animal models. To apply this modality clinically, an interstitial microwave antenna array system has been developed for the delivery of controlled hyperthermia to an intracranial tumor volume, and a Phase I clinical trial(More)
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