Learn More
Membrane fusion is required to establish the morphology and cellular distribution of the mitochondrial compartment. In Drosophila, mutations in the fuzzy onions (fzo) GTPase block a developmentally regulated mitochondrial fusion event during spermatogenesis. Here we report that the yeast orthologue of fuzzy onions, Fzo1p, plays a direct and conserved role(More)
The Saccharomyces cerevisiae Dnm1 protein is structurally related to dynamin, a GTPase required for membrane scission during endocytosis. Here we show that Dnm1p is essential for the maintenance of mitochondrial morphology. Disruption of the DNM1 gene causes the wild-type network of tubular mitochondrial membranes to collapse to one side of the cell but(More)
We sought components that function in morphogenetic events downstream from the segmentation pathway in Drosophila embryos, so we examined mutations that affect development of adult hairs and/or bristles to identify a subset that also affect hairs and denticles on the cuticle of first instar larvae. Mutations at 4 of 23 loci surveyed cause distinct(More)
MIRI is the mid-IR instrument for the James Webb Space Telescope and provides imaging, coronography and integral field spectroscopy over the 5-28µm wavelength range. MIRI is the only instrument which is cooled to 7K by a dedicated cooler, much lower than the passively cooled 40K of the rest of JWST, which introduces unique challenges. The paper will(More)
Agencies charged with collecting tax revenue and enforcing the tax code generally use information provided by taxpayers to decide whether or not to subject individual returns to a variety of review procedures. One consequence of such conditional screening efforts is the creation of incentives for strategic income reporting by individuals who wish to avoid(More)
  • 1