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- Christopher B Buck, Diana V. Pastrana, Douglas R Lowy, John T. Schiller
- Journal of virology
- 2004
Although the papillomavirus structural proteins, L1 and L2, can spontaneously coassemble to form virus-like particles, currently available methods for production of L1/L2 particles capable of… (More)
- Reinhard Kirnbauer, Frank P. Booy, Naiqian Cheng, Douglas R Lowy, John T. Schiller
- Proceedings of the National Academy of Sciences…
- 1992
Infection by certain human papillomavirus types is regarded as the major risk factor in the development of cervical cancer, one of the most common cancers of women worldwide. Analysis of the… (More)
- John T. Schiller, Xavier Castellsagué, Suzanne Marie Garland
- Vaccine
- 2012
End of study analyses of the phase III trials of prophylactic human papillomavirus (HPV) virus-like particle (VLP) vaccines in young women are now largely completed. Two distinct vaccines were… (More)
- Reinhard Kirnbauer, James Taub, +5 authors John T. Schiller
- Journal of virology
- 1993
The L1 genes of two human papillomavirus type 16 (HPV16) isolates derived from condylomata acuminata were used to express the L1 major capsid protein in insect cells via recombinant baculoviruses.… (More)
- Diana V. Pastrana, Christopher B Buck, +6 authors John T. Schiller
- Virology
- 2004
Sensitive high-throughput neutralization assays, based upon pseudoviruses carrying a secreted alkaline phosphatase (SEAP) reporter gene, were developed and validated for human papillomavirus (HPV)16,… (More)
- Rebecca M Richards, Douglas R Lowy, John T. Schiller, Patricia M. Day
- Proceedings of the National Academy of Sciences…
- 2006
Papillomaviruses (PV) comprise a large family of nonenveloped DNA viruses that include the oncogenic PV types that are the causative agents of human cervical cancer. As is true of many animal DNA… (More)
- Petra Lenz, Patricia M. Day, +4 authors John T. Schiller
- Journal of immunology
- 2001
The role of viral structural proteins in the initiation of adaptive immune responses is poorly understood. To address this issue, we focused on the effect of noninfectious papillomavirus-like… (More)
- Francesc Xavier Bosch, Thomas R. Broker, +27 authors Silvia de Sanjosé
- Vaccine
- 2013
Infection with human papillomavirus (HPV) is recognized as one of the major causes of infection-related cancer worldwide, as well as the causal factor in other diseases. Strong evidence for a causal… (More)
- Christopher B Buck, Naiqian Cheng, +4 authors Benes L Trus
- Journal of virology
- 2008
Papillomaviruses are a family of nonenveloped DNA tumor viruses. Some sexually transmitted human papillomavirus (HPV) types, including HPV type 16 (HPV16), cause cancer of the uterine cervix.… (More)
- Patricia M. Day, Douglas R Lowy, John T. Schiller
- Virology
- 2003
In this study we have examined the pathway by which papillomaviruses infect cells, using bovine papillomavirus (BPV) virions and mouse C127 cells as the model system. By confocal microscopy, the… (More)