John S. O’Neill

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The circadian clock is a ubiquitous timekeeping system that organizes the behavior and physiology of organisms over the day and night. Current models rely on transcriptional networks that coordinate circadian gene expression of thousands of transcripts. However, recent studies have uncovered phylogenetically conserved redox rhythms that can occur(More)
Graphical Abstract Highlights d Calcium and the protease SOL trigger TIM degradation in response to thermal input d Thermal TIM degradation resets the Drosophila circadian pacemaker d TIM integrates light and temperature input d In mammals, the SOL homolog also impacts circadian thermal responses In Brief Temperature phase shifts the Drosophila circadian(More)
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