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A case of Castleman's disease localized in the retroperitoneal space is reported. A 29-year-old patient had a mass 15 cm in diameter with radial calcification. After surgical resection, both the patient's anemia and hypergammaglobulinemia disappeared. Castleman's disease should be considered when facing a solid retroperitoneal or mesenteric mass, mainly if(More)
  • J Manuel
  • 1999
Over the past seven years, the U.S. Environmental Protection Agency has consistently ranked indoor air pollution among the top five risks to public health. One of the most dangerous indoor air pollutants is carbon monoxide (CO). CO can be lethal, but perhaps more important, many people suffer ill health from chronic, often undetected exposure to low levels(More)
Exposure to passive (or environmental) tobacco smoke has been implicated in numerous childhood ailments ranging from low birth weight to middle ear disease. Passive smoke has also been suspected , but not proven, to increase the risk of childhood cancer. Clarifying this issue is crucial not only for the protection of chil-dren's health but also for the(More)
We studied several methods for selecting single-nucleotide polymorphisms (SNPs) in a disease association study. Two major categories for analytical strategy are the univariate and the set selection approaches. The univariate approach evaluates each SNP marker one at a time, while the set selection approach tests disease association of a set of SNP markers(More)
  • J Manuel
  • 1999
One study after another is finding strong associations between a variety of human illness and exposure to environmental tobacco smoke (ETS). A 1986 report by the U.S. Surgeon General concluded that ETS is a cause of disease, including lung cancer, in healthy nonsmokers. Other reports have documented causal associations between ETS and lower respiratory(More)
L ong spared the persistent droughts that have plagued the western United States this century, the Southeast suddenly finds itself the most rain-starved region of the country. In the face of this threat, policy makers and utility companies are struggling to identify sensible, sustainable options for managing the region's water. Although there currently is(More)
Inspectors first discovered chemical mixtures leaking from a Freedom Industries storage tank into the Elk River on 9 January 2014. The Elk River provides drinking water for some 300,000 Charleston-area residents, who for several days relied on water that was trucked in by the National Guard and other groups. The disruption cost local businesses more than(More)
In a prospective cohort study, men of Japanese ancestry were clinically examined from 1965 to 1968. For 7,833 of these men, data on black tea consumption habits were recorded. Since 1965, newly diagnosed cancer incidence cases have been identified: 152 colon, 151 lung, 149 prostate, 136 stomach, 76 rectum, 57 bladder, 30 pancreas, 25 liver, 12 kidney and(More)