John S. Manuel

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We studied several methods for selecting single-nucleotide polymorphisms (SNPs) in a disease association study. Two major categories for analytical strategy are the univariate and the set selection approaches. The univariate approach evaluates each SNP marker one at a time, while the set selection approach tests disease association of a set of SNP markers(More)
L ong spared the persistent droughts that have plagued the western United States this century, the Southeast suddenly finds itself the most rain-starved region of the country. In the face of this threat, policy makers and utility companies are struggling to identify sensible, sustainable options for managing the region's water. Although there currently is(More)
Inspectors first discovered chemical mixtures leaking from a Freedom Industries storage tank into the Elk River on 9 January 2014. The Elk River provides drinking water for some 300,000 Charleston-area residents, who for several days relied on water that was trucked in by the National Guard and other groups. The disruption cost local businesses more than(More)