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BACKGROUND Walking speed is a simple and reliable measure of motor function that is negatively associated with adverse health events in older people, including falls, disability, hospital admissions, and mortality. Lead has adverse affects on human health, particularly on the vascular and neurological systems. OBJECTIVE We explored the hypothesis that(More)
OBJECTIVES To examine the relation between occupation and cumulative lead exposure-assessed by measuring bone lead-in a community-dwelling population. METHOD We measured bone lead concentration with K-shell X-Ray Fluorescence in 1320 men in the Normative Aging Study. We categorized job titles into 14 broad US Census Bureau categories. We used ordinary(More)
The management of cancer relies on a combination of imaging and tissue biopsy for diagnosis, monitoring, and molecular classification-based patient stratification to ensure appropriate treatment. Conventional tissue biopsy harvests tumor samples with invasive procedures, which are often difficult for patients with advanced disease. Given the well-recognized(More)
BACKGROUND Tremor is one of the most common neurological signs, yet its etiology is poorly understood. Case-control studies suggest an association between blood lead and essential tremor, and that this association is modified by polymorphisms in the δ-aminolevulinic acid dehydrogenase (ALAD) gene. OBJECTIVE We aimed to examine the relationship between(More)
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