John S Harington

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As an extension of an earlier study covering the 8-year period 1965-71 (t1), the incidence of cancer in black gold miners over a second 8-year period, 1972-79 (t2) has been investigated. The population again totalled 2.9 million man-years of employment, an average of 363,800 men per year. Of the 903 cancers found in t2, primary liver cancer accounted for(More)
The incidence of cancer among the African workers on the gold mines of South Africa has been studied for the period 1964-68. Considering the degree of selection to which they are subjected, the crude cancer rate was unexpectedly high.The most common cancers were those of the liver, the oesophagus, the respiratory system and the bladder. Geographical and(More)
The pattern of cancer in African gold miners over the 8-year period 1964-71, comprising 2,926,461 man-years of employment was studied. Of the 1344 cancers found, primary liver cancer accounted for 52-8%, oesophageal cancer 12-1%, cancer of the respiratory system 5-4% and cancer of the bladder 4-8%. Analysis of the spatial distribution of these four cancers,(More)
The discovery of commercial quantities of gold in the former Transvaal of South Africa in 18961 came twenty years after the exploitation of diamonds in the northen Cape. Labour practices followed the existing migratory pattern for domestic and foreign labour in industry, a pattern which exists to this day. Gold miners, like diamond miners, were accommodated(More)
In in vitro test systems, chrysotile is markedly toxic, causes chromosomal aberrations, and is capable of inducing morphological and preneoplastic transformation. In carefully designed animal experiments, chrysotile produces lung cancer and mesothelioma as effectively as do the amphiboles tested. Human population studies do not refute these experimental(More)
The geographical distribution of lung and stomach cancer among three races in South Africa (Whites, Coloureds and Asians) has been investigated for the years 1968-1972, and the patterns of the occurrence of cases of cancer have been tested stochastically and mapped both separately and together. Information was not available for the Black population.(More)
The geographical distributions of six major causes of cancer mortality in South Africa have been analysed for three population groups: White, Coloured and Asian. Because of the lack of comparable data, the majority Black population is not included. Geographical patterns are compared and discussed in the light of findings from other countries. In several(More)