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From the ability of a concentrated suspension of human erythrocytes to regulate the pH of unbuffered, anisotonic, external media it is possible to calculate the fractional cell volume in which chloride is dissolved. The difference between this volume and the total cell water gives the nonsolvent water (for chloride) of the cell. Nonsolvent water is less(More)
Cancer patients commonly experience a number of symptoms of disease progression and the side-effects of radiation therapy and adjuvant chemotherapy, which adversely impact on their quality of life (QOL). Fatigue is one of the most common and debilitating symptom reported by cancer patients and can affect QOL more than pain. Several recent studies have(More)
Emilio Agostoni Milan Norio Akaike Fukuoka Claude Amiel Paris Stefan Angielski Gdansk Christian M. Bauer Zurich Albert0 Binia Mendoza Jean-Philippe Bonjour Geneva A. Bertrand Brill Worcester Jan Bureg Prague Marc Cantin MontreaJ Rik R. Casteels Louvain Marcelino Cereijido Mexico City Fernando Cervero Bristol John S. Cook Oak Ridge Marcello Costa Adelaide(More)
News in Physiological Sciences (ISSN 0886-1714) is published bimonthly (one volume per year) by the International Union of Physiological Sciences and the American Physiological Society. Copyright 0 1989 by the International Union of Physiological Sciences and the American Physiological Society. Printed in the United States of America. The code at the bottom(More)
Fatigue is a common, often debilitating, side effect of cancer chemotherapy. Pharmacologic vitamin C has been used as an alternative treatment for the disease itself but its effects on fatigue have not often been documented. Here we report on the case of a woman with recurrent breast cancer, undergoing weekly chemotherapy, with lethargy as a major symptom.(More)
The demonstration of five different effects of ultraviolet radiation on the sea urchin's egg indicates that more than one basic photochemical process goes on there. Photorecovery is observed in only one of these. The need for caution in interpreting such effects is obvious. Evidence for a different mechanism for the timing of cleavage in eggs activated by(More)
Medicare Parts A and B engender a system of payment and delivery at odds with that of health maintenance organizations (HMOs). Most evident in the conflicting incentives and requirements levied on primary care physicians participating today in both traditional Medicare and HMOs, the dichotomy has vitiated the promise of managed care and constitutes a(More)
As support grows for greater access to information and data held by governments, so does awareness of the need for appropriate policy, technical and legal frameworks to achieve the desired economic and societal outcomes. Since the late 2000s numerous international organizations, inter-governmental bodies and governments have issued open government data(More)
Following treatment with ultraviolet radiation, human red cells leak cations at accelerated rates which depend on the radiation dose. With one exception (initial Na efflux), these accelerated cation fluxes fit the Ussing flux-ratio criterion for passive diffusion. Na efflux is transiently high, but with time falls to the value expected on the basis of the(More)