John Robert Vane

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The beneficial actions of nonsteroid anti-inflammatory drugs (NSAID) can be associated with inhibition of cyclo-oxygenase (COX)-2 whereas their harmful side effects are associated with inhibition of(More)
Constitutive cyclooxygenase (COX-1; prostaglandin-endoperoxide synthase, EC is present in cells under physiological conditions, whereas COX-2 is induced by some cytokines, mitogens, and(More)