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BPMJ is the leading international journal devoted to publishing articles that provide insight into the management and best practices of key business processes. It does this by staying at the leading edge of theoretical advances in the field, and illustrates the practical relevance of these through case studies and applied examples. The journal helps to(More)
Dual-specificity phosphatase MKP3 down-regulates mitogenic signaling through dephosphorylation of extracellular regulated kinase (ERK). Unlike a simple substrate-enzyme interaction, the noncatalytic, amino-terminal domain of MKP3 can bind efficiently to ERK, leading to activation of the phosphatase catalytic domain by as much as 100-fold toward exogenous(More)
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