John Patrick Sheppard

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OBJECTIVES Previous research has attributed older adults' difficulty with perceiving speech in noise to peripheral hearing loss. However, recent studies have suggested a more complex picture and implicate the central nervous system in sensation and sensory deficits. This study examines the relationship between the neuroanatomical structure of cognitive(More)
We report a novel multisensory decision task designed to encourage subjects to combine information across both time and sensory modalities. We presented subjects, humans and rats, with multisensory event streams, consisting of a series of brief auditory and/or visual events. Subjects made judgments about whether the event rate of these streams was high or(More)
The human brain possesses a remarkable capacity to interpret and recall novel sounds as spoken language. These linguistic abilities arise from complex processing spanning a widely distributed cortical network and are characterized by marked individual variation. Recently, graph theoretical analysis has facilitated the exploration of how such aspects of(More)
Aging is accompanied by substantial changes in brain function, including functional reorganization of large-scale brain networks. Such differences in network architecture have been reported both at rest and during cognitive task performance, but an open question is whether these age-related differences show task-dependent effects or represent only(More)
Stimuli that animals encounter in the natural world are frequently time-varying and activate multiple sensory systems together. Such stimuli pose a major challenge for the brain: Successful multisensory integration requires subjects to estimate the reliability of each modality and use these estimates to weight each signal appropriately. Here, we examined(More)
Acknowledgements: We thank Barry Burbach and Simon Musall for advice on the figures and analyses and Bernardo Sabatini for providing comments on a draft of the paper.. CC-BY-NC-ND 4.0 International license peer-reviewed) is the author/funder. It is made available under a The copyright holder for this preprint (which was not. Abstract Neurons in putative(More)
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