Learn More
OBJECTIVES To describe implementation of a new national preventive programme to reduce cardiovascular morbidity. DESIGN Observational study over 4 years (April 2009--March 2013). SETTING 655 general practices across England from the QResearch database. PARTICIPANTS Eligible adults aged 40-74 years including attendees at a National Health Service (NHS)(More)
OBJECTIVE To derive a new cardiovascular disease risk score (QRISK) for the United Kingdom and to validate its performance against the established Framingham cardiovascular disease algorithm and a newly developed Scottish score (ASSIGN). DESIGN Prospective open cohort study using routinely collected data from general practice. SETTING UK practices(More)
In order to perform a technically adequate clinical electrophysiological procedure it is necessary to calibrate the stimulating and recording equipment. Published standards for the electroretinogram (ERG) [1], electro-oculogram (EOG) [2], visual evoked potential (VEP) [3], pattern ERG (PERG) [4] and guidelines for the multifocal ERG [5] specify stimulus and(More)
OBJECTIVE To develop, validate, and evaluate a new QRISK model to estimate lifetime risk of cardiovascular disease. DESIGN Prospective cohort study with routinely collected data from general practice. Cox proportional hazards models in the derivation cohort to derive risk equations accounting for competing risks. Measures of calibration and discrimination(More)
OBJECTIVES To determine whether a two hour training programme for general practice reception staff could improve uptake in patients who had failed to attend for breast screening, and whether women from different ethnic groups benefited equally. DESIGN Controlled trial, randomised by general practice. SETTING Inner London borough of Newham. SUBJECTS(More)
OBJECTIVE To develop and validate a new diabetes risk algorithm (the QDScore) for estimating 10 year risk of acquiring diagnosed type 2 diabetes over a 10 year time period in an ethnically and socioeconomically diverse population. DESIGN Prospective open cohort study using routinely collected data from 355 general practices in England and Wales to develop(More)
OBJECTIVE To develop and validate version two of the QRISK cardiovascular disease risk algorithm (QRISK2) to provide accurate estimates of cardiovascular risk in patients from different ethnic groups in England and Wales and to compare its performance with the modified version of Framingham score recommended by the National Institute for Health and Clinical(More)
AIM To assess the performance of the QRISK score for predicting cardiovascular disease (CVD) in an independent UK sample from general practice and compare with the Framingham score. DESIGN Prospective open cohort study. SETTING UK general practices contributing to the THIN and QRESEARCH databases. COHORT The THIN validation cohort consisted of 1.07(More)