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OBJECTIVE Obtaining an accurate reduction of the posterior malleolar fragment in high-energy pilon fractures can be difficult through standard anterior or medial incisions, resulting in a less than optimal articular reduction. The purpose of this study was to report on our results using a direct approach with posterior malleolar plating in combination with(More)
The goals of our study were to establish quantitative outcomes for assessing murine knee arthritis and develop an Arthritis Index that incorporates multiple outcomes into a single calculation that provides enhanced sensitivity. Using an accepted model of meniscal/ligamentous injury (MLI)-induced osteoarthritis (OA), we assessed mouse knee arthritis using(More)
Most human papillomavirus (HPV)-associated cervical intraepithelial neoplasia(CIN) lesions in normal women regress spontaneously, but a small number persist and may progress to invasive cancer. To evaluate the role of immunity to HPV and the outcome of CIN and associated HPV infection, we examined cell-mediated immune (CMI) responses to HPV 16 E6 and E7(More)
BACKGROUND Hallux rigidus leads to significant loss of first metatarsophalangeal (MTP) joint motion. Cheilectomy surgery aims to increase motion, decrease pain, and facilitate a return to activity. Limited data exist regarding restoration of dynamic kinematics and loading responses following cheilectomy. This prospective study assessed three-dimensional in(More)
BACKGROUND There has been recent interest in the use of a custom long-stemmed talar component for salvage of failed total ankle replacement or for management of combined ankle and hindfoot pathology. The purpose of this study was to retrospectively review prospective data on patients who underwent total ankle arthroplasty with a custom long-stemmed talar(More)
PURPOSE We previously found that administration of erythropoietin (EPO) shortens the course of recovery after experimental crush injury to the mouse sciatic nerve. The course of recovery was more rapid than would be expected if EPO's effects were caused by axonal regeneration, which raised the question of whether recovery was instead the result of promoting(More)
OBJECTIVE To compare the prevalence of peroneal tendon instability as determined by intraoperative evaluation versus preoperative computed tomography (CT) scans, and to identify specific risk factors that correlate with tendon instability. DESIGN Retrospective comparative study. SETTING Level 1 trauma hospital. PATIENTS Patients with operatively(More)
Heel lifts are commonly prescribed to patients with Achilles tendinopathy, yet little is known about the effect on tendon compressive strain. The purposes of the current study were to (1) develop a valid and reliable ultrasound elastography technique and algorithm to measure compressive strain of human Achilles tendon in vivo, (2) examine the effects of(More)
Introduction Cheilectomy surgery has been shown to provide pain relief for patients with hallux rigidus [1], however limited data exists regarding the effectiveness of this surgery in reestablishing normal first metatarsophalangeal (1st MTP) joint kinematics. A recent dynamic gait study has reported only modest improvement in 1st MTP motion following(More)
OBJECTIVES To assess the healing and radiographic outcomes of displaced and comminuted talar neck fractures treated with medial position screws augmented with lateral minifragment plate fixation. DESIGN Retrospective case series. SETTING Two level I trauma centers. PATIENTS The records of 26 patients with displaced and comminuted talar neck fractures(More)