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- Fredrik Ronquist, John P. Huelsenbeck
- Bioinformatics
- 2003

MrBayes 3 performs Bayesian phylogenetic analysis combining information from different data partitions or subsets evolving under different stochastic evolutionary models. This allows the user to analyze heterogeneous data sets consisting of different data types-e.g. morphological, nucleotide, and protein-and to explore a wide variety of structured models… (More)

- John P. Huelsenbeck, Fredrik Ronquist
- Bioinformatics
- 2001

SUMMARY
The program MRBAYES performs Bayesian inference of phylogeny using a variant of Markov chain Monte Carlo.
AVAILABILITY
MRBAYES, including the source code, documentation, sample data files, and an executable, is available at http://brahms.biology.rochester.edu/software.html.

- Fredrik Ronquist, Maxim Teslenko, +7 authors John P. Huelsenbeck
- Systematic biology
- 2012

Since its introduction in 2001, MrBayes has grown in popularity as a software package for Bayesian phylogenetic inference using Markov chain Monte Carlo (MCMC) methods. With this note, we announce the release of version 3.2, a major upgrade to the latest official release presented in 2003. The new version provides convergence diagnostics and allows multiple… (More)

- J P Huelsenbeck, F Ronquist, R Nielsen, J P Bollback
- Science
- 2001

As a discipline, phylogenetics is becoming transformed by a flood of molecular data. These data allow broad questions to be asked about the history of life, but also present difficult statistical and computational problems. Bayesian inference of phylogeny brings a new perspective to a number of outstanding issues in evolutionary biology, including the… (More)

- Gautam Altekar, Sandhya Dwarkadas, John P. Huelsenbeck, Fredrik Ronquist
- Bioinformatics
- 2004

MOTIVATION
Bayesian estimation of phylogeny is based on the posterior probability distribution of trees. Currently, the only numerical method that can effectively approximate posterior probabilities of trees is Markov chain Monte Carlo (MCMC). Standard implementations of MCMC can be prone to entrapment in local optima. Metropolis coupled MCMC [(MC)(3)], a… (More)

- Johan A A Nylander, Fredrik Ronquist, John P Huelsenbeck, José Luis Nieves-Aldrey
- Systematic biology
- 2004

The recent development of Bayesian phylogenetic inference using Markov chain Monte Carlo (MCMC) techniques has facilitated the exploration of parameter-rich evolutionary models. At the same time, stochastic models have become more realistic (and complex) and have been extended to new types of data, such as morphology. Based on this foundation, we developed… (More)

- D M Hillis, J P Huelsenbeck
- The Journal of heredity
- 1992

DNA sequences and other molecular data compared among organisms may contain phylogenetic signal, or they may be randomized with respect to phylogenetic history. Some method is needed to distinguish phylogenetic signal from random noise to avoid analysis of data that have been randomized with respect to the historical relationships of the taxa being… (More)

- John Huelsenbeck, Bruce Rannala
- Systematic biology
- 2004

What does the posterior probability of a phylogenetic tree mean?This simulation study shows that Bayesian posterior probabilities have the meaning that is typically ascribed to them; the posterior probability of a tree is the probability that the tree is correct, assuming that the model is correct. At the same time, the Bayesian method can be sensitive to… (More)

MrBayes is a program for the Bayesian inference of phylogeny. This manual explains Bayesian inference of phylogeny and how to use the program. The program has a command-line interface and should run on a variety of computer platforms. Note that the computer should be reasonably fast and should have a lot of memory (depending on the size of the data matrix,… (More)

- J P Huelsenbeck, B Rannala
- Science
- 1997

The use of molecular phylogenies to examine evolutionary questions has become commonplace with the automation of DNA sequencing and the availability of efficient computer programs to perform phylogenetic analyses. The application of computer simulation and likelihood ratio tests to evolutionary hypotheses represents a recent methodological development in… (More)