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The Informatics for Integrating Biology and the Bedside (i2b2) is one of the sponsored initiatives of the NIH Roadmap National Centers for Biomedical Computing (http://www.bisti.nih.gov/ncbc/). One of the goals of i2b2 is to provide clinical investigators broadly with the software tools necessary to collect and manage project-related clinical research data(More)
OBJECTIVE Although computerized physician order entry (CPOE) may decrease errors and improve quality, hospital adoption has been slow. The high costs and limited data on financial benefits of CPOE systems are a major barrier to adoption. The authors assessed the costs and financial benefits of the CPOE system at Brigham and Women's Hospital over ten years.(More)
Business intelligence--technology to manage and leverage an organization's data--can enhance healthcare organizations' financial and operational performance and quality of patient care. Effective BI management requires five preliminary steps: Establish business needs and value. Obtain buy-in from managers. Create an end-to-end vision. Establish BI(More)
Tens of thousands of subjects may be required to obtain reliable evidence relating disease characteristics to the weak effects typically reported from common genetic variants. The costs of assembling, phenotyping, and studying these large populations are substantial, recently estimated at three billion dollars for 500,000 individuals. They are also(More)
Judging from the excited rhetoric of some of its enthusiasts, health information technology (HIT) has the power to transport us to almost a dream-like world of health care perfection in which the work of doctors and the care of patients proceed with barely imaginable quality and efficiency. For many physicians, however, especially those in solo or small(More)
The Brigham integrated computing system (BICS) provides nearly all clinical, administrative, and financial computing services to Brigham and Women's Hospital, an academic tertiary-care hospital in Boston. The BICS clinical information system includes a very wide range of data and applications, including results review, longitudinal medical records, provider(More)
BACKGROUND The use of information technology may result in a safer and more efficient health care system. However, consensus does not exist about the structure or costs of a national health information network (NHIN). OBJECTIVES To describe the potential structure and estimate the costs of an NHIN. DESIGN Cost estimates of an NHIN model developed by an(More)