BACKGROUND Alcoholic hepatitis is the most florid presentation of alcohol-related liver disease. In its severe form, defined by a Maddrey's discriminant function (DF) ≥32, the 28-day mortality rate is approximately 35%. A number of potential treatments have been subjected to clinical trials, of which two, corticosteroids and pentoxifylline, may have… (More)
BACKGROUND & AIMS Predicting survival in decompensated cirrhosis (DC) is important in decision making for liver transplantation and resource allocation. We investigated whether high-resolution metabolic profiling can determine a metabolic phenotype associated with 90-day survival. METHODS Two hundred and forty-eight subjects underwent plasma metabotyping… (More)
Overall Goal: Constructed products that are less costly to build and which perform better in terms of durability and maintenance over their life. This goal can be advanced by greater efficiency in the construction process, better architectural and engineering design, and the use of superior performing components supplied by manufacturers.
2. The opinions expressed in this report are those of the authors and do not necessarily reflect the views of the Department of Canadian Heritage or Statistics Canada. Abstract We estimate earnings differentials for knowledge of 13 minority languages in Canada's three largest urban areas. We find that conditional on knowledge of a majority language,… (More)