John N. Oshinski

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The study protocol was HIPAA compliant and institutional review board approved. Informed consent was obtained from all participants. The purpose of the study was to prospectively validate the capability of navigator-echo-gated phase-contrast magnetic resonance (MR) imaging for measurement of myocardial velocities in a phantom and to prospectively use the(More)
BACKGROUND the objective of the study was to determine whether the effects of infarct-related artery (IRA) infusion of autologous bone marrow-derived CD34(+) cells after ST elevation myocardial infarction (STEMI) are dependent on the dose (quantity and mobility) of the cells infused. Beneficial effects of IRA infusion of mononuclear cells after STEMI have(More)
OBJECTIVES This study evaluated whether magnetic resonance imaging (MRI) and magnetic resonance (MR) phase velocity mapping could provide accurate estimates of stenosis severity and pressure gradients in aortic coarctation. BACKGROUND Clinical management of aortic coarctation requires determination of lesion location and severity and quantification of the(More)
PURPOSE To determine whether breath holding can be eliminated in two-dimensional magnetic resonance (MR) imaging of the coronary arteries by using real-time respiratory gating. MATERIALS AND METHODS Thirty-one subjects (20 healthy volunteers, 11 patients) underwent MR imaging. In 13 subjects, a respiratory monitoring belt was used, and in 18 subjects, a(More)
Full explanation for the pathogenesis of syringomyelia (SM), a neuropathology characterized by the formation of a cystic cavity (syrinx) in the spinal cord (SC), has not yet been provided. It has been hypothesized that abnormal cerebrospinal fluid (CSF) pressure, caused by subarachnoid space (SAS) flow blockage (stenosis), is an underlying cause of syrinx(More)
The acute adverse effects of left ventricular (LV) dyssynchrony on cardiac performance were first described in 1925 by Carl Wiggers. In recent years, the accurate diagnosis of LV dyssynchrony has become the focus of myriad publications, driven by the advent of cardiac resynchronization therapy (CRT) to treat heart failure due to severe LV dysfunction in the(More)
BACKGROUND During primary coarctation repair, collateral blood vessels contribute significantly to distal perfusion. We sought to determine if velocity-encoded cine magnetic resonance imaging (VENC-MRI) could provide insight into anatomy and hemodynamics of collateral flow in patients with unrepaired coarctation. METHODS Sixteen patients (median age, 6.2(More)
Although several methods have been used clinically to assess aortic regurgitation (AR), there is no "gold standard" for regurgitant volume measurement. Magnetic resonance phase velocity mapping (PVM) can be used for noninvasive blood flow measurements. To evaluate the accuracy of PVM in quantifying AR with a single imaging slice in the ascending aorta, in(More)
PURPOSE To compare T(1) values of blood and myocardium at 1.5T and 3T before and after administration of Gd-DTPA-BMA in normal volunteers, and to evaluate the distribution of contrast media between myocardium and blood during steady state. MATERIALS AND METHODS Ten normal subjects were imaged with either 0.1 mmol/kg (N = 5) or 0.2 mmol/kg (N = 5) of(More)