Stephanie Clement-Guinaudeau8
Jonathan Suever7
Stamatios Lerakis6
8Stephanie Clement-Guinaudeau
7Jonathan Suever
6Stamatios Lerakis
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There are advantages to conducting cardiovascular magnetic resonance (CMR) studies at a field strength of 3.0 Telsa, including the increase in bulk magnetization, the increase in frequency separation of off-resonance spins, and the increase in T1 of many tissues. However, there are significant challenges to routinely performing CMR at 3.0 T, including the(More)
BACKGROUND Approximately 5% of patients with an acute coronary syndrome are discharged from the emergency room with an erroneous diagnosis of non-cardiac chest pain. Highly accurate non-invasive stress imaging is valuable for assessment of low-risk chest pain patients to prevent these errors. Adenosine stress cardiovascular magnetic resonance (AS-CMR) is an(More)
BACKGROUND Coronary artery motion can decrease image quality during coronary magnetic resonance angiography and computed tomography coronary angiography. PURPOSE To characterize the three-dimensional motion of the coronary arteries along the entire vessel length and to identify the temporal location and duration of periods of relatively low cardiac motion(More)
PURPOSE This study characterized the time course of ventricular remodeling subsequent to reperfused myocardial infarction (MI) in a rat model using cardiac magnetic resonance (MR) imaging. METHODS AND RESULTS Short axis cine MR imaging was used to measure left ventricular ejection fraction (LVEF) and left ventricular volumes in Lewis rats at baseline, 1,(More)
BACKGROUND Significant paravalvular leak (PVL) after transcatheter aortic valve replacement (TAVR) confers a worse prognosis. Symptoms related to significant PVL may be difficult to differentiate from those related to other causes of heart failure. Cardiovascular magnetic resonance (CMR) directly quantifies valvular regurgitation, but has not been(More)
BACKGROUND It is important to understand the relationship between electrical and mechanical ventricular activation in CRT patients. By measuring local electrical activation at multiple locations within the coronary veins and myocardial contraction at the same locations in the left ventricle, we determined the relationship between electrical and mechanical(More)
Considerable efforts have been directed at identifying prognostic markers for rapidly progressing coronary atherosclerotic lesions that may advance into a high-risk (vulnerable) state. Intravascular ultrasound (IVUS) has become a valuable clinical tool to study the natural history of coronary artery disease (CAD). While prospectively IVUS studies have(More)
BACKGROUND Extremes of wall shear stress (WSS) have been associated with plaque progression and transformation, which has raised interest in the clinical assessment of WSS. We hypothesized that calculated coronary WSS is predicted only partially by luminal geometry and that WSS is related to plaque composition. METHODS AND RESULTS Twenty-seven patients(More)
Noninvasive measurement of the speed with which the cerebrospinal fluid (CSF) velocity wave travels through the spinal canal is of interest as a potential indicator of CSF system pressure and compliance, both of which may play a role in the development of craniospinal diseases. However, measurement of CSF velocity wave speed (VWS) has eluded researchers(More)
Wall shear stress (WSS) has been investigated as a potential prospective marker to identify rapidly progressing coronary artery disease (CAD) and potential for lesions to acquire vulnerable characteristics. Previous investigations, however, are limited by a lack of understanding of the focal association between WSS and CAD progression (i.e., data are(More)