John Mullen

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BACKGROUND Carbonic anhydrase enzymes (CA) catalyze the reversible hydration of carbon dioxide to bicarbonate in mammalian cells. Trans-membrane transport of CA-produced bicarbonate contributes significantly to cellular pH regulation. A body of evidence implicates pH-regulatory processes in the hypertrophic growth pathway characteristic of hearts as they(More)
BACKGROUND Involvement of the subcutis by Kaposi sarcoma (KS) occurs primarily when cutaneous KS lesions evolve into deep penetrating nodular tumors. Primary KS of the subcutaneous tissue is an exceptional manifestation of this low-grade vascular neoplasm. CASE PRESENTATION We present a unique case of acquired immune deficiency syndrome (AIDS)-associated(More)
Nonparametric methods are used to measure the impacts of public research expenditures on Australian broadacre agriculture over the 1953-94 period. The data and methods used were unable to recover separate impacts due to extension under several alternative specifications. Preliminary results using both unrestricted and 30 year lagged specifications of the(More)
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