John Mcnamee

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INTRODUCTION Percutaneous stenting is established in the palliation of malignant biliary obstruction. We examined the indications, success rate, complications, and long-term postoperative course of patients undergoing this procedure. METHODS All patients undergoing percutaneous transhepatic cholangiography (PTC) and metal stenting over a 12-month period(More)
The yield of a cigarette is determined by the tobacco blend, the length of the cigarette, the cigarette paper, the filter and air dilution. Cigarette yield has been defined by tradition and by law to be the yield of nicotine, tar and carbon monoxide obtained from a 35 ml puff volume of 2-second duration taken every minute during the burning time of the(More)
Like other organs that exchange substantial quantities of material with blood, the lung accommodates a large two-dimensional surface in a component three-dimensional volume. The lung's structure shows a resemblance to certain one- and two-dimensional mathematical functions that possess plane- and space-filling properties. When viewed from a conventional(More)
The cardiovascular effects of hyperbaric (3 atm abs) air, 100% oxygen, and hyperbaric oxygen (HBO2) at 3 atm abs were investigated in 13 pentobarbital-anesthetized dogs. We measured heart rate, arterial pressure, pulmonary artery pressure, right atrial pressure, left and right ventricular pressure, and cardiac output. From these we determined end diastolic(More)
Development Administration for their assistance and comments. NASDA is also grateful for the contributions of the members of its Research Division who participated in focus group discussions that helped shape the issues and who provided valuable input on the report. We also acknowledge the many incentive program managers who took the time to respond to our(More)
  • J E McNamee
  • 1982
The ease with which plasma proteins and other large solutes enter sheep lung lymph had led previous investigators to conclude that such large molecules probably move through a pathway that has transport properties similar to pores 100 nm or larger in radius. To test this hypothesis, the transport of some very large solutes into lung lymph was measured.(More)
Isogravimetric capillary pressure (Pci), capillary filtration coefficient (CFC), and plasma protein concentration were measured before and during adminisistration of histamine in an isolated, independently perfused canine gracilis muscle. Histamine produced an average decrease in Pci of 14.1 mmHg, an increase in CFC of 36-fold, and an increased rate of(More)
  • J E McNamee
  • 1983
Histamine increases lymph flow and protein flux from the sheep lung. This increase in water and protein movement has been attributed to an increase in lung microvascular permeability-surface area product caused by histamine. Whether it was permeability that was changed or whether it was surface area cannot be discerned from past work. Histamine might(More)