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Reduced oxidative demand or neuronal hypometabolism is a neuroprotective strategy used by several anoxia and hypoxia-tolerant species. The epaulette shark, Hemiscyllium ocellatum inhabits shallow reef platforms that can become hypoxic. Hypoxic pre-conditioning (eight cycles of 0.34 mg O(2)/l for 120 min, 12 h apart) was used to determine whether a reduction(More)
AaSTRACT. Techniques are presented for improving the efficiency ofpnmal-stmplex network codes An adaptive candidate hst, enumerating the pivot variables, is provided. Proper use of this list greatly reduces computation tune (espectaUy m large-scale network problems) and experiential data Js included It is again shown that the number of iterations, i e(More)
We describe a specialization of the primal truncated Newton algorithm for solving nonlinear optimization problems on networks with gains. The algorithm and its implementation are able to capitalize on the special structure of the constraints. Extensive computational tests show that the algorithm is capable of solving very large problems. Testing of numerous(More)