John M Lewin

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PURPOSE To prospectively compare full-field digital mammography (FFDM) with screen-film mammography (SFM) for cancer detection in a screening population. MATERIALS AND METHODS At two institutions, 4,945 FFDM examinations were performed in women aged 40 years and older presenting for SFM. Two views of each breast were acquired with each modality. SFM and(More)
A technique for demonstrating breast cancers, dual-energy contrast agent-enhanced digital subtraction mammography, was performed in 26 subjects with mammographic or clinical findings that warranted biopsy. The technique consists of high-energy and low-energy digital mammography after administration of iodinated contrast agent. Weighted subtraction of the(More)
OBJECTIVE The purpose of this work is to compare full-field digital mammography and screen-film mammography for the detection of breast cancer in a screening population. SUBJECTS AND METHODS Full-field digital mammography was performed in addition to screen-film mammography in 6736 examinations of women 40 years old and older presenting for screening(More)
Despite its technical advantages, early clinical trials comparing digital mammography with film mammography for screening have been somewhat disappointing. Digital mammography,however, is in its infancy and can be expected to improve more rapidly than film mammography. Some areas of improvement being observed now include the development of new detector(More)
PURPOSE To compare the diagnostic accuracy of contrast-enhanced digital mammography (CEDM) and contrast-enhanced tomosynthesis (CET) to dynamic contrast enhanced breast MRI (DCE-MRI) using a multireader-multicase study. METHODS Institutional review board approval and informed consents were obtained. Total 185 patients (mean age 51.3) with BI-RADS 4 or 5(More)
PURPOSE The authors describe modifications to previously developed cascaded systems analysis to include the anatomical noise in evaluation of dual-energy noise reduction techniques. Previous models have ignored the anatomical noise in theoretical analysis of noise reduction techniques. The inclusion of anatomical noise leads to more accurate estimation of(More)
RATIONALE AND OBJECTIVES To evaluate the comparative performance of high-fidelity liquid crystal display (LCD) and cathode ray tube (CRT) devices for mammography applications, and to assess the impact of LCD viewing angle on detection accuracy. MATERIALS AND METHODS Ninety 1 k x 1 k images were selected from a database of digital mammograms: 30 without(More)
Abstracts must be structured into Background, Methods, Results, Conclusions. Please remember to also update the Abstract details on the submission page. The abstract has now been restructured. Competing interests Please include a Competing interests section between the Conclusions and Authors' contributions. A competing interests section has now been added,(More)
In contrast-enhanced mammography (CEM), the dual-energy dual-exposure technique, which can leverage existing conventional mammography infrastructure, relies on acquiring the low- and high-energy images using two separate exposures. The finite time between image acquisition leads to motion artifacts in the combined image. Motion artifacts can lead to greater(More)