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PURPOSE This study describes the preparation and characterization of a controlled release formulation of granulocyte-macrophage colony-stimulating factor (GM-CSF) encapsulated in poly(glycolide-co-D,L-lactide) (PLGA) and poly(D,L-lactide) (PLA) microspheres. METHODS GM-CSF was encapsulated in PLGA/PLA microspheres by a novel silicone oil based phase(More)
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