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  • Ahmad S. Khalil, Mitchell Guttman, +10 authors John L. Rinn
  • Medicine, Biology
  • Proceedings of the National Academy of Sciences
  • 2009 (First Publication: 14 July 2009)
  • We recently showed that the mammalian genome encodes >1,000 large intergenic noncoding (linc)RNAs that are clearly conserved across mammals and, thus, functional. Gene expression patterns haveExpand
  • John L. Rinn, Howard Y. Chang
  • Biology, Medicine
  • Annual review of biochemistry
  • 2012 (First Publication: 4 June 2012)
  • The central dogma of gene expression is that DNA is transcribed into messenger RNAs, which in turn serve as the template for protein synthesis. The discovery of extensive transcription of large RNAExpand