John L. Richardson

Deuan C Jones1
Mohamed H Abdille1
1Deuan C Jones
1Mohamed H Abdille
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Trypanothione reductase (TryR) is a key validated enzyme in the trypanothione-based redox metabolism of pathogenic trypanosomes and leishmania parasites. This system is absent in humans, being replaced with glutathione and glutathione reductase, and as such offers a target for selective inhibition. As part of a program to discover antiparasitic drugs, the(More)
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