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  • A. Emre Sayan, Thomas R L Griffiths, +15 authors Eugene Tulchinsky
  • Medicine, Biology
  • Proceedings of the National Academy of Sciences
  • 2009 (First Publication: 1 September 2009)
  • The epithelial-mesenchymal transition (EMT) contributes to cancer metastasis. Two ZEB family members, ZEB1 and ZEB2(SIP1), inhibit transcription of the E-cadherin gene and induce EMT in vitro.Expand
  • Jakob Mejlvang, Marina Kriajevska, +5 authors Eugene Tulchinsky
  • Medicine, Biology
  • Molecular biology of the cell
  • 2007 (First Publication: 1 November 2007)
  • Zinc finger transcription factors of the Snail/Slug and ZEB-1/SIP1 families control epithelial-mesenchymal transitions in development in cancer. Here, we studied SIP1-regulated mesenchymal conversionExpand
  • Henriette Andersen, Jakob Mejlvang, +6 authors Eugene Tulchinsky
  • Biology, Medicine
  • Molecular and Cellular Biology
  • 2005 (First Publication: 15 October 2005)
  • ABSTRACT The invasion suppressor protein, E-cadherin, plays a central role in epithelial cell-cell adhesion. Loss of E-cadherin expression or function in various tumors of epithelial origin isExpand
  • Svetlana Tarabykina, Thomas R L Griffiths, Eugene Tulchinsky, John Kilian Mellon, Igor B. Bronstein, Marina Kriajevska
  • Biology, Medicine
  • Current cancer drug targets
  • 2007 (First Publication: 1 May 2007)
  • S100A4 (also known as Mts1, metastasin, p9Ka, pEL98, CAPL, calvasculin, Fsp-1, placental calcium-binding protein) belongs to the family of EF-hand calcium-binding proteins, whose expression isExpand
    Over the last decade, epidemiological, experimental and clinical studies have implicated oxidative stress in the development and progression of prostate cancer. Oxidative stress may be linked to theExpand
  • V M Tut, Ken Braithwaite, Brian J. Angus, David E. Neal, John Lunec, John Kilian Mellon
  • Medicine
  • British Journal of Cancer
  • 2001 (First Publication: 1 January 2001)
  • Normal cell proliferation is closely regulated by proteins called cyclins. One of these, cyclin D1, in combination with its corresponding cyclin-dependent kinase (cdk), is essential for G1/S phaseExpand