John K Hayes

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BACKGROUND The concept of antiinflammatory effects of volatile anesthetics is well established in vitro and in some organ systems. Their protective role in lung injury, however, remains to be elucidated. The authors hypothesized that in the lung, isoflurane pretreatment may attenuate neutrophil infiltration and reduce endotoxin-induced injury. METHODS(More)
BACKGROUND The present study was designed to investigate in a focal cerebral ischemia model the influence of 2APH, a competitive NMDA receptor antagonist, on the cerebral blood flow of cat cortex, given intravenously before cerebral ischemia. METHODS Thirty-four male cats weighing 2.5 to 3.5 kg were anesthetized with halothane and then randomly assigned(More)
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